Fig. 3
In vivo and ex vivo change in T1 relaxation time for RF and chemoablation lesion cores relative to myocardial T1 as measured on Day 0. T1 measured in vivo a demonstrates an average drop of 149 ± 49 ms (19 ± 7%) in RF ablation lesion cores and 316 ± 53 ms (40 ± 7%) for chemoablation lesions cores relative to normal myocardium. T1 measured ex vivo b demonstrates an average drop of 110 ± 21 ms (18 ± 3%) in RF ablation lesion cores and 257 ± 50 ms (42 ± 6%) for chemoablation lesions cores relative to normal myocardium. All statistical comparisons indicated significant differences (Student’s t-test, paired, Bonferroni correction). Overall, chemoablation produced 2.1 × and 2.3 × greater effect in vivo and ex vivo in myocardial T1 at lesion cores, respectively