Skip to main content

Table 2 Anatomic and tissue properties of cardiac metastases

From: Risk stratification of cardiac metastases using late gadolinium enhancement cardiovascular magnetic resonance: prognostic impact of hypo-enhancement evidenced tumor avascularity

 

Heterogeneously enhancing

CMET+ (n = 59)

Diffusely enhancing

CMET+ (n = 53)

p

Clinical characteristics

   

 Cancer etiologies

   

  Sarcoma

24% (14)

15% (8)

0.25

  Lung

15% (9)

17% (9)

0.80

  Genitourinary

19% (11)

11% (6)

0.28

  Gastrointestinal

14% (8)

11% (6)

0.72

  Skin/Melanoma

7% (4)

19% (10)

0.05

  Lymphoma

3% (2)

13% (7)

0.08

  Endocrine

10% (6)

6% (3)

0.50

 Cardiovascular risk factors

   

  Hypertension

42% (26)

38% (20)

0.50

  Hyperlipidemia

27% (16)

28% (15)

0.89

  Diabetes mellitus

10% (6)

11% (6)

0.84

  Smoking

24% (14)

40% (21)

0.07

 Cardiopulmonary disease

   

  Coronary artery disease

12% (7)

9% (5)

0.68

  Atrial fibrillation/flutter

10% (6)

15% (8)

0.43

  Pulmonary disease

3% (2)

2% (1)

1.00

  Pulmonary hypertension

15% (9)

9% (5)

0.35

Anatomic properties

   

 Lesion location

   

  Left ventricle

36% (21)

28% (15)

0.41

  Right ventricle

34% (20)

40% (21)

0.53

  Left atrium

20% (12)

25% (13)

0.60

  Right atrium

24% (14)

38% (20)

0.11

  Pericardium

32% (19)

26% (14)

0.50

  Left-sided

53% (31)

47% (25)

0.57

  Right-sided

49% (29)

68% (36)

0.04

  Bilateral

17% (10)

23% (12)

0.45

  Multi-chamber

25% (15)

36% (19)

0.23

 Intra-cavitary

   

  Left ventricle

9% (5)

8% (4)

1.00

  Right ventricle

22% (13)

25% (13)

0.76

  Left atrium

17% (10)

21% (11)

0.61

  Right atrium

17% (10)

26% (14)

0.22

 Lesion number (1 | 2 |≥ 3)

78% | 19% | 3%

70% | 19% | 11%

0.26

 Lesion size

   

  Area (cm2)

16.0 ± 20.8

10.1 ± 16.0

0.10

  Perimeter (cm)

15.3 ± 11.3

13.3 ± 12.9

0.39

  Maximal length (cm)

5.1 ± 3.7

3.7 ± 2.8

0.02

  Orthogonal length (cm)

3.0 ± 2.0

2.4 ± 1.8

0.11

  Perimeter/min Length

5.0 ± 1.7

7.3 ± 8.8

0.06

 Pericardial effusion

37% (22)

21% (11)

0.06

 Tissue properties

   

  Contrast-to-noise ratio (CNR)

20.5 ± 15.0

7.4 ± 9.1

 < 0.001

  Signal-to-noise ratio (SNR)

33.1 ± 20.1

44.5 ± 41.2

0.08

  Blood pool normalized

0.6 ± 0.2

0.8 ± 0.3

 < 0.001