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Table 5 Univariable and multivariable logistic regression analysis for the composite endpoint

From: Multimodal assessment of right ventricle overload-metabolic and clinical consequences in pulmonary arterial hypertension

Value

Univariable analysis

HR

95% CI

p-value

WHO Class

12.34

1.53–95.49

0.01

Age

0.98

0.93–1.03

0.50

BSA

0.03

0.01–2.88

0.13

BNP

1.03

0.99–1.08

0.13

6MWT

0.99

0.97–1

0.05

PET parameters

   

SUVRV/SUVLV ratio

17.84

1.48–214.8

0.02

CMR parameters

   

RVEF

0.83

0.71–0.96

0.01

RV mass/BSA

1.09

1.06–1.18

0.05

PAC

0.50

0.23–1.21

0.09

RHC parameters

   

mPAP

1.67

1.04–1.30

0.008

PCWP

1.04

0.74–1.47

0.79

DPG

1.31

0.99–1.44

0.05

RAP

1.61

1.03–2.51

0.03

CI

0.24

0.05–1.07

0.06

PVR

1.56

1.08–2.25

0.01

SvO2

0.99

0.87–1.21

0.89

RV GLS

1.38

1.05–1.81

0.01

RV GLS/PASP*

19.88

3.59–1099

0.003

RV GLS/PVR

2.31

1.20–4.45

0.01

RV GLS*PAC

1.09

1.01–1.18

0.01

  1. 6MWD 6-minute walking test distance, BSA body surface area, BNP brain natriuretic peptide, CI cardiac index, DPG diastolic pulmonary gradient, GLS global longitudinal strain, mPAP mean pulmonary artery pressure, PAC pulmonary arterial compliance, PASP pulmonary artery systolic pressure, PCWP pulmonary capillary wedge pressure, PET positron emission tomography, PVR pulmonary vascular resistance, RAP right atrial pressure, RV right ventricle, RVEF right ventricle ejection fraction, SUV standardized uptake value, SvO2 mixed venous oxygen saturation, WHO World Health Organisation
  2. *Remained statistically significant in multivariable stepwise regression model included PAH prognostic parameters (WHO class, SUVRV/SUVLV, RVEF, mPAP), (R2 = 0.68, p < 0.001)
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Journal of Cardiovascular Magnetic Resonance

ISSN: 1532-429X

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