Table 4 Univariable and multivariable linear regression analysis for factors associated with serological cardiac biomarkers according to different CKD stages

Hematocrit (%)

− 0.015 (− 0.106 to 0.083)

0.816

NS

NS

− 0.189 (− 0.263 to − 0.052)

0.004

− 0.233 (− 0.289 to − 0.099)

< 0.001

hs-CRP (Lg10)

0.062 (− 0.049 to 0.139)

0.344

NS

NS

0.133 (0.005 to 0.216)

0.041

NS

NS

LVEDV (ml/m²)

0.255 (0.108 to 0.315)

< 0.001

0.166 (0.034 to 0.242)

0.1

0.337 (0.204 to 0.433)

< 0.001

NS

NS

LV mass index (g/m²)

0.154 (0.022 to 0.225)

0.018

NS

NS

0.135 (0.007 to 0.239)

0.038

NS

NS

LVEF (%)

− 0.253 (− 0.299 to − 0.102)

0.001

NS

NS

− 0.427 (− 0.490 to − 0.280)

< 0.001

− 0.398 (− 0.465 to − 0.254)

< 0.001

GLS (%)

0.221 (0.069 to 0.251)

0.001

NS

NS

0.345 (0.15 to 0.385)

< 0.001

NS

NS

LA (cm²)

0.18 (0.038 to 0.238)

0.007

NS

NS

0.298 (0.149 to 0.369)

< 0.001

0.208 (0.079 to 0.282)

0.001

IVC variation (%)

0.108 (− 0.02 to 0.231)

0.099

NS

NS

− 0.015 (− 0.160 to 0.126)

0.815

NS

NS

LGE (presence)

0.387 (0.189 to 0.356)

< 0.001

0.345 (0.155 to 0.331)

< 0.001

0.291 (0.135 to 0.332)

< 0.001

NS

NS

Native T1 (ms)

0.059 (− 0.060 to 0.157)

0.368

NS

NS

0.269 (0.140 to 0.378)

< 0.001

NS

NS

Native T2 (ms)

0.096 (− 0.028 to 0.193)

0.141

NS

NS

0.114 (− 0.013 to 0.237)

0.08

NS

NS

Hematocrit (%)

− 0.097 (− 0.277 to 0.074)

0.256

NS

NS

− 0.165 (− 0.290 to 0.003)

0.055

NS

NS

hs-CRP (Lg10)

0.255 (0.090 to 0.416)

0.003

NS

NS

0.389 (0.190 to 0.451)

< 0.001

NS

NS

LVEDV (ml/ m²)

0.207 (0.037 to 0.324)

0.014

NS

NS

0.381 (0.161 to 0.390)

< 0.001

NS

NS

LV mass index (g/m²⁾

0.291 (0.133 to 0.463)

< 0.001

0.218 (0.018 to 0.428)

< 0.001

0.308 (0.123 to 0.400)

< 0.001

NS

NS

LVEF (%)

− 0.271 (− 0.381 to − 0.096)

0.001

NS

NS

− 0.417 (− 0.419 to − 0.191)

< 0.001

NS

NS

GLS (%)

0.281 (0.119 to 0.444)

0.001

NS

NS

0.467 (0.260 to 0.514)

< 0.001

0.319 (0.117 to 0.405)

< 0.001

LA (cm²)

0.307 (0.098 to 0.423)

0.002

0.242 (0.035 to 0.375)

0.002

0.500 (0.227 to 0.477)

< 0.001

0.311 (0.095 to 0.343)

0.001

IVC variation (%)

0.02 (− 0.222 to 0.282)

0.813

NS

NS

− 0.065 (− 0.293 to 0.132)

0.454

NS

NS

LGE (presence)

0.256 (0.087 to 0.394)

0.002

NS

NS

0.368 (0.162 to 0.412)

< 0.001

NS

NS

Native T1 (ms)

0.189 (0.033 to 0.379)

0.025

NS

NS

0.389 (0.201 to 0.475)

< 0.001

0.308 (0.129 to 0.407)

< 0.001

Native T2 (ms)

0.217 (0.057 to 0.410)

0.01

NS

NS

0.304 (0.126 to 0.418)

< 0.001

NS

NS

Hematocrit (%)

− 0.5 (− 0.73 to − 0.318)

< 0.001

− 0.307 (− 0.537 to − 0.107)

0.004

− 0.42 (− 0.736 to − 0.239)

< 0.001

− 0.303 (− 0.575 to − 0.128)

0.003

hs-CRP (Lg10)

0.168 (− 0.061 to 0.432)

0.139

NS

NS

0.167 (− 0.080 to 0.489)

0.157

NS

NS

LVEDV (ml/m²)

0.369 (0.160 to 0.586)

0.001

NS

NS

0.497 (0.327 to 0.786)

< 0.001

NS

NS

LV mass index (g/m²)

0.389 (0.165 to 0.546)

< 0.001

NS

NS

0.575 (0.385 to 0.776)

< 0.001

0.390 (0.183 to 0.604)

0.001

LVEF (%)

− 0.135 (− 0.368 to 0.091)

0.234

NS

NS

− 0.305 (− 0.599 to 0.090)

0.009

NS

NS

GLS (%)

0.251 (0.037 to 0.548)

0.026

NS

NS

0.401 (0.237 to 0.796)

< 0.001

NS

NS

LA (cm²)

0.407 (0.179 to 0.707)

0.001

0.284 (0.097 to 0.522)

0.005

0.400 (0.181 to 0.784)

0.002

NS

NS

IVC variation (%)

− 0.106 (− 0.275 to 0.100)

0.354

NS

NS

− 0.237 (− 0.430 to − 0.007)

0.043

NS

NS

LGE (presence)

0.174 (− 0.064 to 0.506)

0.127

NS

NS

0.310 (0.119 to 0.750)

0.008

NS

NS

Native T1 (ms)

0.388 (0.189–0.657)

< 0.001

NS

NS

0.549 (0.423 to 0.904)

< 0.001

0.334 (0.154 to 0.660)

0.002

Native T2 (ms)

0.583 (0.415–0.799)

< 0.001

0.417 (0.219 to 0.650)

< 0.001

0.480 (0.314 to 0.793)

< 0.001

NS

NS