Fig. 2

Representative Findings in Canines—Subject-Specific T2* vs. 20-ms Absolute T2* Cut-off for Hemorrhage Characterization. Representative T2* maps and corresponding LGE acquired at 1.5T in a canine with hemorrhagic MI in the LAD territory in the acute and chronic phases A. Ex-vivo T2* maps, along with histological validation of IMH are shown in panel B. Perl’s stain showed the presence of the iron deposition in the infarcted myocardium (arrow) which is not evident in the remote territory. In panels A, B both raw and processed image sets [using ssT2* (second column) and aT2* < 20 ms (third column)] are shown side-by-side for comparison. Panel C shows magnified representation of T2 maps from panels A, B. Note that similar to patients, although the location of IMH is the same with both ssT2* and aT2* < 20 ms, the extent of IMH identified using aT2* < 20 ms approach are visually smaller (see red arrows) compared to that determined using ssT2*