Reproducibility of global and segmental myocardial strain using cine DENSE at 3 T: a multicenter cardiovascular magnetic resonance study in healthy subjects and patients with heart disease

Auger, Daniel A.; Ghadimi, Sona.; Cai, Xiaoying; Reagan, Claire E.; Sun, Changyu; Abdi, Mohamad; Cao, Jie Jane; Cheng, Joshua Y.; Ngai, Nora; Scott, Andrew D.; Ferreira, Pedro F.; Oshinski, John N.; Emamifar, Nick; Ennis, Daniel B.; Loecher, Michael; Liu, Zhan-Qiu; Croisille, Pierre; Viallon, Magalie; Bilchick, Kenneth C.; Epstein, Frederick H.

doi:10.1186/s12968-022-00851-7

Journal of Cardiovascular Magnetic Resonance

Table 2 Summary of correlation, Bland–Altman, CV and ICC results. Global E_cc and E_rr values are averaged over 3 slices (base, mid-ventricle and apex)

From: Reproducibility of global and segmental myocardial strain using cine DENSE at 3 T: a multicenter cardiovascular magnetic resonance study in healthy subjects and patients with heart disease

Group	Variability	r²	Bias	Limits (Lower:Upper)	CV	ICC	95% CI of ICC
E_cc Global	Intra-User	0.89	0.000	− 0.03:0.03	3.0 ± 0.3	0.93 ± 0.01	0.90–0.97
	Inter-User-Same-Site	0.89	0.010	− 0.03:0.02	3.7 ± 0.4	0.93 ± 0.03	0.85–1.0
	Inter-User-Different-Site	0.90	0.005	− 0.02:0.03	4.0 ± 0.5	0.93 ± 0.03	0.87–0.99
	Inter-User-Human-DL	0.88	0.001	− 0.03:0.03	3.8 ± 0.3	0.88 ± 0.04	0.82–0.92
	Inter-Scan	0.80	0.001	− 0.03:0.03	5.0 ± 0.3	0.85 ± 0.04	0.78–0.93
E_ll Global	Intra-User	0.90	0.002	− 0.01:0.02	2.9	0.94	–
	Inter-User	0.79	− 0.003	− 0.03:0.02	4.5	0.88	–
	Inter-Site	0.8	0.006	− 0.02:0.03	5.5	0.88	–
	Inter-Session	0.73	0.001	− 0.03:0.03	5.2	0.84	–
E_rr Global	Intra-User	0.85	0.003	− 0.13:0.12	24.6 ± 4.7	0.92 ± 0.05	0.88–0.95
	Inter-User-Same-Site	0.61	− 0.004	− 0.18:0.19	47 ± 16.5	0.75 ± 0.09	0.68–0.83
	Inter-User-Different-Site	0.67	− 0.009	− 0.19:0.17	34 ± 12.2	0.80 ± 0.04	0.73–0.86
	Inter-User-Human-DL	0.69	0.005	− 0.16:0.17	19.7 ± 6.0	0.82 ± 0.04	0.91–0.96
	Inter-Scan	0.19	0.014	− 0.32:0.29	33 ± 7.5	0.74 ± 0.07	0.66–0.81
E_cc Segmental	Intra-User	0.88	0.000	− 0.04:0.04	6.4 ± 2.1	0.91 ± 0.03	0.93–0.90
	Inter-User-Same-Site	0.84	0.003	− 0.05:0.04	8.3 ± 2.8	0.86 ± 0.07	0.9–0.82
	Inter-User-Different-Site	0.84	0.005	− 0.05:0.04	8.9 ± 2.5	0.86 ± 0.08	0.81–0.90
	Inter-User-Human-DL	0.79	0.001	− 0.05:0.05	8.7 ± 3.7	0.83 ± 0.05	0.79–0.88
	Inter-Scan	0.74	0.001	− 0.05:0.06	11.4 ± 6.5	0.77 ± 0.09	0.72–0.82
Torsion Global	Intra-User	0.98	0.002	− 0.25:0.26	2.48	0.99	–
	Inter-User-Same-Site	0.94	0.030	− 0.48:0.54	5.41	0.97	–
	Inter-User-Different-Site	0.93	− 0.061	− 0.67:0.54	5.83	0.96	–
	Inter-User-Human-DL	0.99	0.050	− 0.49:0.60	2.97	0.99	–
	Inter-Scan	0.72	0.006	− 1.13:1.14	21.2	0.86	–

CV, coefficient of variation; DL, deep learning; ICC, intra-class correlation coefficient; Ecc, circumferential strain; Ell longitudinal strain; Err radial strain

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ISSN: 1532-429X

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