From: Multiparametric mapping by cardiovascular magnetic resonance imaging in cardiac tumors
Parameters | Benign cardiac tumors (n = 54) | Primary cardiac malignant tumors (n = 26) | Control subjects (n = 50) |
---|---|---|---|
Age, years | 52 (34–65) | 48 (30–57) | 51 (42–60) |
Males, n (%) | 22 (41)‡ | 11 (42)* | 24 (48) |
BMI, kg/m2 | 22.9 ± 5.8 | 21.5 ± 4.8 | 22.4 (20.8–25.2) |
SBP, mmHg | 126 ± 17.3 | 108 ± 11.8* | 122.4 ± 10.3 |
DBP, mmHg | 81.4 ± 11.1 | 70.5 ± 10.4* | 74.3 ± 7.8 |
Heart rate | 83.0 ± 15.5‡ | 96.5 ± 17.9*‡ | 75.3 ± 9.6 |
Hct | 0.39 ± 0.07‡ | 0.35 ± 0.08*‡ | 0.43 ± 0.03 |
cTnT, g/L | 12.2 (7.0–45.7) | 12.1 (9.8–22.2) | – |
NT-proBNP, pg/mL | 245 (57–871) | 515 (295–1954) | – |
AFP | 2.2 (1.7–3.0) | 2.4 (1.8–3.7) | – |
CEA | 1.7 (0.7–2.7) | 1.4 (0.7–3.2) | – |
CA19-9 | 9.9 (3.7–17.7) | 7.4 (5.4–12.8) | – |
CA125 | 21.0 (11.0–45.1) | 150 (32.5–457)* | – |
Cardiac structure and function | |||
 LVEDVi, mL/m2 | 75.3 ± 20.2 | 68.4 ± 25.4 | 76.6 ± 12.2 |
 LVESVi, mL/m2 | 30.5 ± 12.1 | 28.0 ± 10.8 | 28.5 ± 7.4 |
 LVEF, % | 59.7 ± 9.2 | 59.0 ± 7.6 | 63.4 ± 5.3 |
 LVmassi, g/m2 | 63.4 ± 26.1 | 60.5 ± 30.4 | 45.5 ± 8.2 |
 RVEDVi, mL/m2 | 67.2 ± 18.6 | 66.7 ± 36.4 | 70.7 ± 16.5 |
 RVESVi, mL/m2 | 35.6 ± 17.7 | 33.3 ± 21.7 | 31.7 ± 10.3 |
 RVEF, % | 53.9 ± 11.0 | 53.6 ± 10.6 | 57.2 ± 14.2 |
Characteristics of tumors | |||
 Location | |||
  LA, n (%) | 14 (26) | 4 (15) | – |
  RA, n (%) | 16 (30) | 12 (46) | – |
  LV, n (%) | 11 (20) | 2 (8) | – |
  RV, n (%) | 11 (20) | 7 (27) | – |
  Valves, n (%) | 2 (4) | 1 (4) | – |
 Mobility, n (%) | 37 (69) | 4 (15)* | – |
 Invasiveness, n (%) | 3 (6) | 20 (77)* | – |
 Irregular border, n (%) | 10 (19) | 16 (62)* | – |
 Longest diameter, cm | 3.3 (1.9–4.6) | 6.5 (4.4–7.4)* | – |
 Shortest diameter, cm | 2.0 (1.3–3.0) | 3.2 (2.4–4.9)* | – |
 Pericardial effusion, n (%) | 6 (11) | 13 (54)* | – |
 Tissue characteristics | |||
  T1-weighted, n (%) | |||
   Hypointense | 3 (6) | 2 (3) | – |
   Isointense | 48 (89) | 21 (81) | – |
   Hyperintense | 3 (6) | 3 (12) | – |
  T2-weighted, n (%) | |||
   Hypointense | 3 (6) | 2 (3) | – |
   Isointense | 13 (24) | 9 (35) | – |
   Hyperintense | 38 (70) | 15 (58) | – |
  First-pass perfusion, n (%) | |||
   None | 2 (4) | 0 (0) | – |
   Hypoperfusion | 32 (59) | 13 (50) | – |
   Isoperfusion | 8(15) | 7 (27) | – |
   Hyperperfusion | 12 (22) | 6 (23) | – |
  LGE | |||
   None | 14 (26) | 3 (12) | – |
   Homogeneous | 13 (24) | 3 (12) | – |
   Heterogeneous | 27 (50) | 20 (77) | – |
  Mapping parameters | |||
   T1 mapping (pre)-mass, msa | 1684 ± 450 | 1627 ± 410 | – |
   T1 mapping (post)-mass, msa | 433 ± 123 | 412 ± 135 | – |
   T2 mapping-mass, msa | 59 ± 25 | 63 ± 34 | – |
Tissue characteristics of myocardium | |||
 T1 mapping (pre-contrast) | |||
  T1 mapping-mean, ms | 1260 ± 46‡ | 1360 ± 61*‡ | 1206 ± 44 |
  T1 mapping-peri, ms | 1266 ± 47 | 1388 ± 96* | – |
  T1 mapping-remote, ms | 1253 ± 51 | 1337 ± 67* | – |
 T1 mapping (post-contrast) | |||
  T1 mapping-mean, ms | 536 ± 63‡ | 544 ± 83‡ | 503 ± 52 |
  T1 mapping-peri, ms | 546 ± 66 | 540 ± 82 | – |
  T1 mapping-remote, ms | 544 ± 63 | 577 ± 75 | – |
 T2 mapping | |||
  T2 mapping-mean, ms | 41 ± 3.0‡ | 42 ± 3.2‡ | 38 ± 3.1 |
  T2 mapping-peri, ms | 40 ± 3.1 | 42 ± 3.2 | – |
  T2 mapping-remote, ms | 41 ± 3.0 | 41 ± 3.7 | – |
 ECV | |||
  ECV-mean, % | 30 ± 2.5‡ | 35 ± 5.2*‡ | 27 ± 3.0 |
  ECV-peri, % | 29 ± 3.0 | 36 ± 6.9* | – |
  ECV-remote, % | 29 ± 2.7 | 33 ± 5.8* | – |
 LGE | |||
  Presence, n (%) | 0 | 3 (12%) | – |