Differences in blood flow dynamics between balloon- and self-expandable valves in patients with aortic stenosis undergoing transcatheter aortic valve replacement

Table 5 Changes of 4D flow CMR parameters before and after TAVR

Parameter	BEV (n = 58)	SEV (n = 40)	P ^a value	Mean difference ^b	P ^c value
Vortical flow score	− 0.03 ± 1.09	− 0.23 ± 0.97	0.46	− 0.32 (− 0.63 to − 0.02)	0.036
Helical flow score	− 0.22 ± 0.86	− 0.85 ± 0.80	< 0.001	− 0.44 (− 0.70 to − 0.17)	0.0014
Flow eccentricity score	− 0.11 ± 0.79	− 0.50 ± 0.88	0.037	− 0.37 (− 0.67 to − 0.07)	0.018
Average WSS, Pa	− 0.6 (− 2.1 to 0.5)	− 1.8 (− 3.5 to − 0.8)	0.006	− 1.29 (− 1.97 to − 0.61)	0.003
Peak WSS, Pa	− 5.7 (− 18.0 to 5.3)	− 11.5 (− 27.3 to 2.9)	0.16	− 6.67 (− 12.03 to − 1.29)	0.016
Systolic EL (AAo), mW	− 9.5 (− 20.5 to − 2.1)	− 6.7 (− 18.1 to − 0.22)	0.51	− 2.57 (− 8.24 to 3.10)	0.37
Diastolic EL(AAo), mW	− 0.7 (− 3.3 to 1.6)	− 0.1 (− 1.7 to 3.3)	0.28	0.35 (− 3.03 to 3.73)	0.84
Systolic EL (LV), mW	0.2 (− 1.4 to 3.2)	0.2 (− 0.4 to 2.5)	0.83	− 0.65 (− 2.88 to 1.58)	0.56
Diastolic EL (LV), mW	0.6 (− 2.7 to 3.5)	− 0.5 (− 2.0 to 1.9)	0.39	− 1.88 (− 4.72 to 0.97)	0.19

Continuous variables are presented as means ± standard deviations if normally distributed, and median (interquartile range) if not normally distributed. An analysis of covariance (ANCOVA) was performed using the individual pre-TAVR values of 4D flow CMR as covariates. a, P-value for the Mann–Whitney test; b, least squares mean difference using ANCOVA; c, P-value for ANCOVA. The other abbreviations are the same as those in Tables 1 and 3

ISSN: 1532-429X