Technical development and feasibility of a reusable vest to integrate cardiovascular magnetic resonance with electrocardiographic imaging

Table 1 Baseline characteristics

Group	Younger age participants (HV) n = 27	Older age participants (MyoFit46) n = 50	p value*
Demographics
Age, years	38.9 ± 8.5	77.0 ± 0.1	< 0.001
Male, n	9 [35]	26 [51]	0.23
BSA, m²	1.79 ± 0.25	1.82 ± 0.17	0.57
Heart rate, bpm	68 ± 11	63 ± 9.7	0.08
Past medical history
T2DM	0 (0)	2 (4)	NA
HTN	0 (0)	15 (30)	NA
Chol	0 (0)	18 (36)	NA
MI	0 (0)	1 (2)	NA
IHD	0 (0)	3 (6)	NA
AF	0 (0)	0 (0)	NA
AB	0 (0)	2 (4)	NA
ACEi	0 (0)	11 (22)	NA
BB	0 (0)	4 (4)	NA
CCB	0 (0)	6 (6)	NA
CMR parameters
LAVi,ml	21 ± 3.9	22 ± 6.8	0.28
LVEDVi, ml	81 (12)	75 (12)	0.21
MAPSE, mm	18 ± 4.3	15 ± 2.9	0.002
LVEF, %	72 (7.2)	72 (7.8)	0.28
LVSVi, ml	41 (15)	40 (15)	0.71
RVEDVi, ml	99 (19)	83 (21)	< 0.001
TAPSE, mm	23 ± 3.7	23 ± 3.9	0.58
RVEF, %	58 ± 4.3	60 ± 5.2	0.068
12-lead ECG
RR, ms	929 ± 139	941 ± 133	0.75
PR, ms	160 ± 23	174 ± 37	0.06
QRS, ms	94 ± 8.6	100 ± 15	0.03
QTc, ms	410 ± 20	422 ± 26	0.001
ECGI parameters
Amp, mV	1.41 ± 0.34	1.41 ± 0.37	0.97
AT, ms	41 (10)	44 (7.7)	0.30
RT, ms	289 ± 20	296 ± 21	0.002
ARI, ms	235 ± 18	250 ± 21	0.002
AT_d, ms	11 (3.5)	13.6 (4.4)	0.01
RT_d, ms	28 (8.9)	31 (13)	0.09
ARI_d, ms	32 ± 9.0	37 ± 12	0.04
G_AT, ms/mm	0.34 (0.12)	0.40 (0.13)	0.01
G_RT, ms/mm	0.77 (0.23)	0.92 (0.40)	0.03
G_ARI, ms/mm	0.92 ± 0.27	1.12 ± 0.40	0.01
Frac, n	1.004 (0.01)	1.003 (0.01)	0.88

Statistics are presented as mean ± SD, median (IQR) or n [%]
Significant p values are highlighted in bold
Amp amplitude, AB alpha-blocker, ACEi angiotensin converting enzyme inhibitor, AT activation time, ARI activation recovery interval, BB beta-blocker, BSA body surface area, CCB calcium channel blocker, Chol hypercholesterolaemia, HTM hypertension, ECG electrocardiogram, Frac fractionation, G_AT, G_RT, G_ARI spatial gradient of AT, RT and ARI respectively, IHD ischaemic heart disease, LAVi BSA-indexed left atrial volume, LVEF left ventricular ejection fraction, LVEDVi BSA-indexed left ventricular end diastolic volume, LVSVi BSA-indexed left ventricular systolic volume, MAPSE mitral annular plane systolic excursion, MI myocardial infarction, RVEDVi BSA-indexed right ventricular end diastolic volume, RVEF right ventricular ejection fraction; RT repolarization time, TAPSE tricuspid annular plane systolic excursion, T2DM type 2 diabetes, AT_d, RT_d, ARI_d global dispersion of AT, RT and ARI respectively
^*Differences between younger and older participants were measured using unpaired t-test, Mann–Whitney U or Chi-squared test as appropriate

ISSN: 1532-429X